Dr. Brett Sperry

Brett W. Sperry, MD, is a cardiologist specializing in advanced heart failure and transplant cardiology. He serves as Associate Professor of Medicine at the University of Missouri-Kansas City School of Medicine and practices at Saint Luke’s Mid America Heart Institute in Kansas City, Missouri. His clinical focus includes advanced heart failure care, heart transplantation and mechanical circulatory support, and cardiovascular imaging and diagnostics for complex cardiomyopathies. Dr. Sperry’s research interests center on noninvasive cardiovascular imaging, therapeutic innovation in advanced heart failure and transplant cardiology, and clinical pathways for infiltrative and restrictive cardiomyopathies. His academic work reflects a strong commitment to improving diagnosis, treatment strategies, and multidisciplinary care for patients with complex cardiovascular disease. He earned his medical degree from Georgetown University School of Medicine, completed his residency in internal medicine at MedStar Health/Georgetown University Hospital, and went on to fellowship training in cardiovascular medicine and advanced heart failure and transplantation at Cleveland Clinic.